They were forbidden by the Holy Spiritto preach the word in Asia. After they had come to Mysia, they tried to go into Bithynia,but the Spirit did not permit them.”
Our destination, as well as our departure, must be governed by the Spirit. How intriguing that the Spirit actually forbade them to preach the word in Asia and Bithynia! This ought to be proof enough that “need,” in and of itself, is insufficient guidance. The only thing that matters is being sent, and it is critical that we go only where the Spirit sends us.
The apostles were indeed sent forth by the Spirit, yet that same Spirit did not permit them to just go wherever they pleased. Later we see that Paul indeed went to Asia and a tremendous work was founded. This tells us that a “no” today does not mean a “no” is forever; nevertheless, when the Spirit forbids us, we dare not take matters into our own hands and go where we have not been sent.
Source: Embrace the Cross by Chip Brogden